4a-Hydroxycholesterol

4α-Hydroxycholesterol (CAS 34310-86-6) (5mg) is a synthetic oxysterol (molecular formula C₁₇H₄₆O₂) that serves as a valuable research reagent. It is an endogenous cholesterol metabolite produced by CYP3A enzymes and has been identified as a potential ligand for the nuclear liver X receptor (LXR), as well as a novel endogenous marker of CYP3A activity. This compound is used in studies on cholesterol homeostasis, membrane fluidity, inflammation, and atherosclerosis.

Keywords: 4α-Hydroxycholesterol, 4 alpha hydroxy cholesterol, oxysterol research reagent, CYP3A endogenous marker, LXR ligand, cholesterol metabolite, C27H46O2 oxysterol